Infrapyloric lymph node dissection in right hemicolectomy for colon cancer: Should prophylactic resection be recommended?. (1st March 2021)

• Record Type: Journal Article
• Authors: Sun, Yueming; Zhang, Dongsheng; Feng, Yifei; Wang, Yong; Xu, Ziwei; Tang, Junwei; Huang, Yuanjian; Zhang, Chuan
• Other Names: Zheng Min‐Hua guestEditor.
• Is Part Of: Journal of surgical oncology. Volume 123(2021)Supplement 1
• Page Start: S30
• Page End: S35
• Publication Date: 2021-03-01
• Subjects: colon cancer -- hepatic flexure -- lymph node; Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.26388
• Languages: English
• ISSNs: 0022-4790

Abstract

Abstract: Background and Objectives: Infrapyloric lymph node dissection in right colon cancer patients remains controversial. We aimed to investigate the pattern of infrapyloric lymph node metastasis in right colon cancer patients. Methods: Clinical and pathological data of 140 colon cancer patients who underwent radical right hemicolectomy and infrapyloric lymph node dissection were retrospectively examined. Patient characteristics, intraoperative conditions, postoperative recovery information, postoperative pathological findings, and follow‐up data were examined. Results: About 19, 44, 73, and 4 patients had tumors located in the cecum, ascending colon, hepatic flexure, and right side of the transverse colon, respectively. The median number of harvested lymph nodes and that of positive lymph nodes were 24 (16–30) and 1 (0–7.75), respectively. The lymph node metastasis rate was 41.43% (58/140). The corresponding values for infrapyloric lymph nodes were 3 (1–4), 0 (0–0), and 0.71% (1/140), respectively. The median follow‐up duration was 19 (0–65) months in 131 (93.6%) patients. The 5‐year overall and disease‐free survival rates were 86.3% and 73.5%, respectively. Conclusion: Given the low rate of infrapyloric lymph node metastasis in right colon cancer, lymph node dissection is recommended in patients with locally advanced colon cancer at the hepatic flexure and those with suspected infrapyloric lymph node metastasis.