Manipulation of autophagy in cancer cells: an innovative strategy to fight drug resistance. (June 2013)
- Record Type:
- Journal Article
- Title:
- Manipulation of autophagy in cancer cells: an innovative strategy to fight drug resistance. (June 2013)
- Main Title:
- Manipulation of autophagy in cancer cells: an innovative strategy to fight drug resistance
- Authors:
- Aredia, Francesca
Scovassi, A Ivana - Abstract:
- Autophagy is a catabolic process activated by stress conditions and nutrient deprivation, to which it reacts by promoting the degradation of damaged organelles and misfolded/aggregated proteins, as well as generating new energetic pools. Paradoxically, in cancer cells, which signal the dangerous microenvironment occurring during clinical therapies, autophagy could promote their proliferation and sustain drug resistance. Special attention is given to autophagy manipulation in order to counteract drug resistance of cancer cells. This article describes the basic properties of autophagy and focuses on the strategies of manipulating it.
- Is Part Of:
- Future medicinal chemistry. Volume 5:Number 9(2013)
- Journal:
- Future medicinal chemistry
- Issue:
- Volume 5:Number 9(2013)
- Issue Display:
- Volume 5, Issue 9 (2013)
- Year:
- 2013
- Volume:
- 5
- Issue:
- 9
- Issue Sort Value:
- 2013-0005-0009-0000
- Page Start:
- 1009
- Page End:
- 1021
- Publication Date:
- 2013-06
- Subjects:
- Pharmaceutical chemistry -- Periodicals
615.19005 - Journal URLs:
- http://www.future-science-group.com/m/102 ↗
http://www.future-science.com/ ↗ - DOI:
- 10.4155/fmc.13.85 ↗
- Languages:
- English
- ISSNs:
- 1756-8919
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 16672.xml