Fabrication of Cupric oxide decorated β-cyclodextrin nanocomposite solubilized Nafion as a high performance electrochemical sensor for l-tyrosine detection. (January 2020)

• Record Type: Journal Article
• Authors: Karthika, A.; Rosaline, D. Rani; Inbanathan, S.S.R.; Suganthi, A.; Rajarajan, M.
• Is Part Of: Journal of physics and chemistry of solids. Volume 136(2020)
• Publication Date: 2020-01
• Subjects: Electrochemical sensor -- l-tyrosine -- Glassy carbon electrode -- Low detection limit -- Sensitivity; Solids -- Periodicals; Solides -- Périodiques; Solids; Periodicals; 530.41
• DOI: 10.1016/j.jpcs.2019.109145
• Languages: English
• ISSNs: 0022-3697

Abstract

Abstract: In the present work, a novel cupric oxide decorated on β-cyclodextrin (CuO/β-CD) nanocomposite was synthesized by sonochemical method. The CuO/β-CD nanocomposites were characterized by UV–vis, Raman, FT-IR, FE-SEM, mapping analysis, XRD techniques. Fascinatingly, the CuO/β-CD nanocomposite Nafion (Nf) solubilized modified glassy carbon electrode (CuO/β-CD/Nf/GCE) has exhibited a superior electrocatalytic activity towards the l -tyrosine, when compared to the modified β-CD, CuO, and bare GCE electrodes. Besides, the electrochemical sensing performance was revealed as an excellent amperometric i-t current response for the l -tyrosine determination with a wide linear range from 0.01 to 100 μM, high sensitivity 442 μA μM −1 cm 2 and low detection limit (LOD) 0.0082 μM. Furthermore, it manifested a good selectivity, repeatability, stability, and reproducibility. In addition, the CuO/β-CD/Nf modified GCE electrode shows good sensibleness for the l -tyrosine detection of blood serum, food samples, and urine samples. Graphical abstract: Image 1 Highlights: Cupric oxide decorated β-cyclodextrin nanocomposite was synthesized using sonochemical method. Cupric oxide decorated β-cyclodextrin nanocomposite shows enhanced electrocatalytic detection of l -tyrosine. It is owing to better electron transfer efficiency and high surface area of the nanocomposite modified electrode. Amperometric technique is adopted to identify low detection of l -tyrosine in the presence of real samples.