Recent advances in transition-metal-catalyzed asymmetric reactions of diazo compounds with electron-rich (hetero-) arenes. Issue 24 (13th June 2018)

• Record Type: Journal Article
• Authors: Li, Yi-Pan; Li, Zi-Qi; Zhu, Shou-Fei
• Is Part Of: Tetrahedron letters. Volume 59:Issue 24(2018)
• Page Start: 2307
• Page End: 2316
• Publication Date: 2018-06-13
• Subjects: Asymmetric catalysis -- Diazo compounds -- Electron-rich (hetero-) arenes -- Transition-metal-catalysts -- Carbenes; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.04.055
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: The title reaction becomes a new growth point in diazo chemistry. Significant progresses have been made in the title reaction. The title reaction is a powerful tool for constructing useful chiral building blocks. The title reaction was applied in the total synthesis of natural products. The development of catalysts ensures the success of the title reaction. Abstract: The transition-metal-catalyzed reaction of diazo compounds with arenes or heteroarenes is an efficient and straightforward approach to functionalize aromatic compounds. This digest summarizes recent progresses on transition-metal-catalyzed asymmetric reactions of diazo compounds with electron-rich (hetero-) arenes, including C–H functionalization, cascade reaction, cyclopropanation, cycloaddition, Buchner reaction and intramolecular dearomatization.