An evaluation of the antiaging properties of strawberry hydrolysate treatment enriched with L‐ascorbic acid applied with microneedle mesotherapy. (16th April 2018)

• Record Type: Journal Article
• Authors: Markiewicz, Agata; Zasada, Malwina; Erkiert‐Polguj, Anna; Wieckowska‐Szakiel, Marzena; Budzisz, Elzbieta
• Is Part Of: Journal of cosmetic dermatology. Volume 18:Number 1(2019:Feb.)
• Page Start: 129
• Page End: 135
• Publication Date: 2018-04-16
• Subjects: antioxidant -- combination therapy -- microneedling -- skin aging -- skin penetration -- vitamin C; Skin -- Diseases -- Treatment -- Periodicals; Lasers in surgery -- Periodicals; Skin -- Pathophysiology -- Periodicals; Surgery, Plastic -- Periodicals; 616.5
• DOI: 10.1111/jocd.12545
• Languages: English
• ISSNs: 1473-2130

Abstract

Summary: Background: Mature skin is characterized by a loss of elasticity, hyperpigmentation, and dehydration. L‐ascorbic acid stimulates the synthesis of collagen type I, inhibits melanogenesis, and helps to maintain correct skin hydration. Combining microneedle mesotherapy with the application of preparations rich in vitamin C results in better therapeutic effects due to the improved absorption of active substances. The study evaluates the effectiveness of the application of strawberry hydrolysate enriched with L‐ascorbic acid using microneedle mesotherapy. Materials and methods: Seventeen volunteers aged 45‐70 years underwent a series of four microneedle mesotherapy treatments with vitamin C serum, performed every 10 days. The 20% L‐ascorbic acid solution (pH = 3.5) was prepared immediately before application. After the treatment, the participants gave a subjective assessment of the effectiveness. Cutometer ® was used to measure skin elasticity and firmness, Corneometer ® to measure skin hydration, and Mexameter ® skin tone. Results: The results of the survey showed improvements in skin hydration and elasticity. In vivo studies confirmed the effectiveness of serum and the impact of the active substance on skin firmness and elasticity, the degree of hydration and skin tone. Conclusion: Microneedling with vitamin C improves skin tone, hydratation and firmness, and decreases the visibility of hyperpigmentation.