Idiopathic stromal keratitis resembling central toxic keratopathy. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Wagh, Vijay Kumar; de Benito‐Llopis, Laura; O'Brart, David P.S.
• Is Part Of: Journal of cataract and refractive surgery. Volume 41:Issue 7(2015)
• Publication Date: 2015-07
• Subjects: 617.7
• DOI: 10.1016/j.jcrs.2015.06.001
• Languages: English
• ISSNs: 0886-3350

Abstract

Abstract : N/A: A 28‐year‐old previously emmetropic woman presented with a 2‐day history of bilateral photophobia and blurred vision. She had no history of corneal surgery or contact lens use. Snellen uncorrected distance visual acuity (UDVA) was 6/12 bilaterally. Bilateral anterior stromal infiltration of the central cornea was seen, with no overlying epithelial defect and intact sensation. There was a marked hyperopic shift, central corneal thinning, and associated keratometric flattening. The patient was started on topical corticosteroids. Over 12 weeks, the UDVA returned to 6/5 with emmetropization of the refractive status and thickening of the central cornea. The clinical findings in our patient resemble those of central toxic keratopathy (CTK) in post‐refractive‐surgery cases, suggesting a similar mechanism. To our knowledge, this is the first report of a patient presenting with a CTK‐like syndrome in the absence of previous keratorefractive surgery or contact lens use. The pathophysiology of this condition remains elusive and requires further investigation. Financial Disclosure : No author has a financial or proprietary interest in any material or method mentioned.