Late‐onset progression of keratoconus after therapy with selective tissue estrogenic activity regulator. Issue 1 (January 2019)

• Record Type: Journal Article
• Authors: Torres‐Netto, Emilio A.; Randleman, Bradley J.; Hafezi, Nikki L.; Hafezi, Farhad
• Is Part Of: Journal of cataract and refractive surgery. Volume 45:Issue 1(2019)
• Publication Date: 2019-01
• Subjects: 617.7
• DOI: 10.1016/j.jcrs.2018.08.036
• Languages: English
• ISSNs: 0886-3350

Abstract

Abstract : N/A: We describe the association of rapid progression of keratoconus in a 49‐year‐old woman on selective tissue estrogenic activity regulator (STEAR) therapy for endometriosis. Approximately 4 months after initiation of therapy with STEAR therapy and 3 months after ovariectomy, Scheimpflug images showed a massive increase in the previously stable ectasia. During this period, the maximum increase in the keratometry values was 2.7 diopters (D) in the right eye and 3.8 D in the left eye. Corneal crosslinking (CXL) was performed in both eyes. This resulted in excessive flattening of 5.5 D in the right eye and 6.1 D in the left eye at 9 months postoperatively. Patients having STEAR therapy must be monitored closely for corneal changes.