Dietary Inflammatory Index and the Risk of Frailty Among Older Adults: A Systematic Review and Meta-Analysis. (August 2021)

• Record Type: Journal Article
• Authors: Moradi, Sajjad; Hadi, Amir; Mohammadi, Hamed; Asbaghi, Omid; Zobeiri, Mehdi; Marx, Wolfgang; Entezari, Mohammad Hassan
• Is Part Of: Research on aging. Volume 43:Number 7/8(2021)
• Page Start: 323
• Page End: 331
• Publication Date: 2021-08
• Subjects: dietary inflammatory index -- frailty risk -- systematic review -- meta-analysis; Old age -- Periodicals; Gerontology -- United States -- Periodicals; 305.2605
• DOI: 10.1177/0164027520948176
• Languages: English
• ISSNs: 0164-0275

Abstract

A systematic review and meta-analysis was conducted to comprehensively examine the association between Dietary Inflammatory Index (DII®) score and risk of frailty. Frailty risk were available from five studies comprising 13, 908 older adults. Furthermore, frailty related parameters were extacted from two studies with 7, 539 individuals. A pooled adjusted odds ratio analysis indicated that there was an association between DII® score and frailty risk (OR = 1.24, 95%CI: 1.6–1.33, P < 0.001, I 2 = 0.0%). The results of frailty related parameters demonstrated that DII® score was associated with weakness risk (OR = 1.12, 95%CI: 1.05–1.19, P = 0.014, I 2 = 0.0%), but not other frailty-related parameters including exhaustion, low BMI or low physical activity. The results of this meta-analysis suggest that older adults who exhibit higher DII® scores have an increased frailty risk. Further prospective cohort studies with longer follow-up periods, are needed to support this possible association between DII® score and frailty risk.