Impact of meibomian gland width on successful contact lens use. Issue 6 (December 2019)
- Record Type:
- Journal Article
- Title:
- Impact of meibomian gland width on successful contact lens use. Issue 6 (December 2019)
- Main Title:
- Impact of meibomian gland width on successful contact lens use
- Authors:
- Pucker, Andrew D.
Jones-Jordan, Lisa A.
Kunnen, Carolina M.E.
Marx, Sebastian
Powell, Daniel R.
Kwan, Justin T.
Srinivasan, Sruthi
Sickenberger, Wolfgang
Jones, Lyndon - Abstract:
- Abstract: Purpose: To evaluate meibomian gland (MG) width and determine its impact on successful contact lens (CL) use and ocular health. Methods: A five-site study was conducted by recruiting 18- to 45-year-old subjects who had dropped out of CLs because of discomfort. CL dropouts were compared to age- and sex-matched successful CL wearers. Right eyes were evaluated for tear break-up time, tear meniscus height, MG expressibility, meibum quality, and meibography. Central MG widths were evaluated with a custom MATLAB program. Results: CL dropouts (n = 56) and successful CL (n = 56) wearers had similar grades for upper (p = 1.0) and lower (p = 0.22) MG atrophy, upper (p = 0.07) and lower (p = 0.89) MG tortuosity, and upper (p = 0.92) and lower (p = 0.97) MG widths. Upper eyelid MG widths were narrower than lower eyelid MG widths (p = 0.03). Upper and lower MG tortuosity (p < 0.001) and widths (p = 0.03) were associated, but not atrophy (p = 0.42). Lower eyelid MG widths were associated with MG expressibility (p = 0.01), but MG widths were not with any other factors. Conclusions: Successful CL wear does not appear to be clinically influenced by MG width or other measures of MG structural integrity. Lower eyelid MGs were wider than upper eyelid MGs and narrower lower eyelid MGs were associated with worse MG expressibility, suggesting that narrower MGs may produce abnormal meibum. Data also suggests that MG factors of both eyelids should be evaluated in practice.
- Is Part Of:
- Contact lens & anterior eye. Volume 42:Issue 6(2019)
- Journal:
- Contact lens & anterior eye
- Issue:
- Volume 42:Issue 6(2019)
- Issue Display:
- Volume 42, Issue 6 (2019)
- Year:
- 2019
- Volume:
- 42
- Issue:
- 6
- Issue Sort Value:
- 2019-0042-0006-0000
- Page Start:
- 646
- Page End:
- 651
- Publication Date:
- 2019-12
- Subjects:
- Meibomian gland width -- Meibomian gland atrophy -- Meibomian gland dysfunction -- Contact lens dissatisfaction -- Image analysis
Anterior segment (Eye) -- Periodicals
Contact lenses -- Periodicals
Segment antérieur (Œil) -- Périodiques
Lentilles de contact -- Périodiques
617.752305 - Journal URLs:
- http://firstsearch.oclc.org/journal=1367-0484;screen=info;ECOIP ↗
http://www.sciencedirect.com/science/journal/13670484 ↗
http://www.contactlensjournal.com/ ↗
http://www.clinicalkey.com/dura/browse/journalIssue/13670484 ↗
http://www.clinicalkey.com.au/dura/browse/journalIssue/13670484 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.clae.2019.06.004 ↗
- Languages:
- English
- ISSNs:
- 1367-0484
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3424.971000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 16616.xml