The Radiology of Osteoporotic Vertebral Fractures Revisited. (27th February 2019)
- Record Type:
- Journal Article
- Title:
- The Radiology of Osteoporotic Vertebral Fractures Revisited. (27th February 2019)
- Main Title:
- The Radiology of Osteoporotic Vertebral Fractures Revisited
- Authors:
- Lentle, Brian
Koromani, Fjorda
Brown, Jacques P.
Oei, Ling
Ward, Leanne
Goltzman, David
Rivadeneira, Fernando
Leslie, William D
Probyn, Linda
Prior, Jerilynn
Hammond, Ian
Cheung, Angela M.
Oei, Edwin H. - Abstract:
- ABSTRACT: Until recently there has been little evidence available to validate any method by which to make an accurate diagnosis of an osteoporotic vertebral fractures (OVFs) from plain radiographs. In part this reflects a lack of a completely satisfactory "gold standard, " but primarily it relates to the absence of well‐designed prospective studies in this context. Historically, OVFs were recognized by evidence of macroscopic structural failure in vertebrae using the criteria applied elsewhere in the skeleton. This comprised altered alignment, fragmentation, cortical disruptions, and breaks, among other changes. However, these morphological criteria were replaced by vertebral morphometry, referring to the use of quantitative or quasi‐quantitative measurement tools for fracture diagnosis. Vertebral morphometry emerged as an understanding of and treatment for osteoporosis evolved, mainly in response to the need for expeditious assessments of large numbers of spine images for epidemiological and pharmaceutical purposes. Although most of the descriptions of such morphometric tools have stressed that they were not to be applied to clinical diagnosis with respect to individual patients, this constraint has been widely disregarded. Here we review the major attempts to develop a diagnostic strategy for OVF and describe their characteristics in adults and children. Recent evidence suggests that morphometric (quantitative; ie, based on measurement of dimensions and shape description)ABSTRACT: Until recently there has been little evidence available to validate any method by which to make an accurate diagnosis of an osteoporotic vertebral fractures (OVFs) from plain radiographs. In part this reflects a lack of a completely satisfactory "gold standard, " but primarily it relates to the absence of well‐designed prospective studies in this context. Historically, OVFs were recognized by evidence of macroscopic structural failure in vertebrae using the criteria applied elsewhere in the skeleton. This comprised altered alignment, fragmentation, cortical disruptions, and breaks, among other changes. However, these morphological criteria were replaced by vertebral morphometry, referring to the use of quantitative or quasi‐quantitative measurement tools for fracture diagnosis. Vertebral morphometry emerged as an understanding of and treatment for osteoporosis evolved, mainly in response to the need for expeditious assessments of large numbers of spine images for epidemiological and pharmaceutical purposes. Although most of the descriptions of such morphometric tools have stressed that they were not to be applied to clinical diagnosis with respect to individual patients, this constraint has been widely disregarded. Here we review the major attempts to develop a diagnostic strategy for OVF and describe their characteristics in adults and children. Recent evidence suggests that morphometric (quantitative; ie, based on measurement of dimensions and shape description) criteria are inferior to morphologic (qualitative; ie, based on structural integrity) vertebral damage assessment in identifying people with low bone density and at an increased risk of future fracture. Thus there is now an evidentiary basis for suggesting that morphological assessment is the preferred strategy for use in diagnosing OVF from radiographs. © 2019 American Society for Bone and Mineral Research. … (more)
- Is Part Of:
- Journal of bone and mineral research. Volume 34:Number 3(2019)
- Journal:
- Journal of bone and mineral research
- Issue:
- Volume 34:Number 3(2019)
- Issue Display:
- Volume 34, Issue 3 (2019)
- Year:
- 2019
- Volume:
- 34
- Issue:
- 3
- Issue Sort Value:
- 2019-0034-0003-0000
- Page Start:
- 409
- Page End:
- 418
- Publication Date:
- 2019-02-27
- Subjects:
- SPINE -- VERTEBRAL FRACTURES -- SPINAL FRACTURES -- OSTEOPOROSIS -- DIAGNOSIS -- MORPHOMETRIC DEFORMITIES -- MORPHOLOGIC VERTEBRAL FRACTURES -- EPIDEMIOLOGY
Bones -- Metabolism -- Periodicals
Mineral metabolism -- Periodicals
612.392 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1523-4681 ↗
http://www.jbmr-online.com ↗ - DOI:
- 10.1002/jbmr.3669 ↗
- Languages:
- English
- ISSNs:
- 0884-0431
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4954.255530
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 16602.xml