Biomedical Applications: Gram‐Negative Bacteria Targeting Mediated by Carbohydrate–Carbohydrate Interactions Induced by Surface‐Modified Nanoparticles (Adv. Funct. Mater. 48/2019). (26th November 2019)

• Record Type: Journal Article
• Authors: Capeletti, Larissa Brentano; de Oliveira, Jessica Fernanda Affonso; Loiola, Lívia Mesquita Dias; Galdino, Flávia Elisa; da Silva Santos, Denys Ewerton; Soares, Thereza Amélia; de Oliveira Freitas, Raul; Cardoso, Mateus Borba
• Is Part Of: Advanced functional materials. Volume 29:Number 48(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-11-26
• Subjects: bacteria targeting -- carbohydrate–carbohydrate interactions -- colloidal stability -- lypopolysaccharide -- nanoparticles; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970325
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number 1904216, Mateus Borba Cardoso and co‐workers demonstrate that nanoparticles fuctionalized with gluconamide moieties present selective targeting ability to Gram‐negative bacteria membranes and no significant toxicity to mammalian or red blood cells. In addition, gluconamide functionality also provides tunable antibiotic delivery abilities, high stability in complex biological media, and lack of non‐specific protein adhesion.