Front Cover: Nanoscopic Structural Fluctuations of Disassembling Microtubules Revealed by Label‐Free Super‐Resolution Microscopy (Small Methods 4/2021). Issue 4 (14th April 2021)

• Record Type: Journal Article
• Authors: Vala, Milan; Bujak, Łukasz; García Marín, Antonio; Holanová, Kristýna; Henrichs, Verena; Braun, Marcus; Lánský, Zdeněk; Piliarik, Marek
• Is Part Of: Small methods. Volume 5:Issue 4(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-04-14
• Subjects: dynamic instability -- iSCAT -- microtubules -- scattering anisotropy -- super‐resolution microscopy; Nanotechnology -- Methodology -- Periodicals; Nanotechnology -- Periodicals; Periodicals; 620.5028
• DOI: 10.1002/smtd.202170012
• Languages: English
• ISSNs: 2366-9608

Abstract

Abstract : In article number 2000985, Marek Piliarik and co‐workers develop a new light microscopy technique for label‐free detection and localization of conformation changes and subsequent depolymerization of tubulin segments from a tip of a disassembling microtubule. High‐speed imaging of the transient structural fluctuations suggests a stochastic mechanism of the microtubule dynamic instability.