Convenient synthesis of benzo[4, 5]thiazolo[2, 3-c][1, 2, 4]triazoles with 1 mol% CuCl2·2H2O as catalyst in water. Issue 3 (18th December 2014)

• Record Type: Journal Article
• Authors: Wen, Li-Rong; Li, Shou-Lei; Zhang, Jian; Li, Ming
• Is Part Of: Green chemistry. Volume 17:Issue 3(2015)
• Page Start: 1581
• Page End: 1588
• Publication Date: 2014-12-18
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c4gc02156h
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A synthesis of benzo[4, 5]thiazolo[2, 3- c ][1, 2, 4]triazoles has been developed from hydrazides and o -bromo-arylisothiocyanates with 1 mol% CuCl2 ·2H2 O as catalyst in water. Abstract : A convenient and efficient procedure for the synthesis of benzo[4, 5]thiazolo [2, 3- c ][1, 2, 4]triazoles has been developed via a tandem intermolecular C–N bond and intramolecular C–S bond formation sequence from o -bromo-arylisothiocyanates and aroylhydrazides. A series of benzo[4, 5]thiazolo[2, 3- c ][1, 2, 4]triazoles were provided in excellent overall yields with 1 mol% CuCl2 ·2H2 O/1 mol% 1, 10-phenanthroline as the catalyst and water as the solvent.