Transcutaneous near‐infrared spectroscopy (NIRS) for monitoring kidney and liver allograft perfusion. Issue 5 (26th January 2021)

• Record Type: Journal Article
• Authors: Ghidini, Filippo; Benetti, Elisa; Zucchetta, Pietro; Amigoni, Angela; Gamba, Piergiorgio; Castagnetti, Marco
• Is Part Of: International journal of clinical practice. Volume 75:Issue 5(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-01-26
• Subjects: Clinical medicine -- Periodicals; Medicine -- Periodicals; 610.5
• DOI: 10.1111/ijcp.14034
• Languages: English
• ISSNs: 1368-5031

Abstract

Abstract: Background: The use of transcutaneous near‐infrared spectroscopy (NIRS) for monitoring the perfusion of kidney and liver allografts has been proposed in the last years. This device might detect an early decrease in allograft oxygenation allowing prompt detection of vascular complications. Methods: A systematic review of the literature about the use of transcutaneous NIRS in monitoring allograft perfusion was performed according to the PRISMA guidelines. Results: The authors screened 1313 papers. The search yielded five pertinent articles. Three of them reported the experience of NIRS in kidney transplantation and the other two dealt with its use in liver transplantation, for a total of 55 paediatric patients and 121 adults. In the studies concerning kidney transplantation, NIRS measurements were significantly related to serum creatinine, estimated glomerular filtration rate (eGFR), urinary neutrophil gelatinase‐associated lipocalin (u‐NGAL), serum lactate, resistive index assessed by Doppler‐ultrasonography and systolic blood pressure. The two studies dealing with liver transplantation found a significant decrease in liver regional oxygenation, assessed by NIRS, before the occurrence of vascular complications. Conclusions: Preliminary studies have related NIRS monitoring to kidney and liver allograft perfusion, both in adults and children. Further investigation is needed to establish the normal range of NIRS values and the factors influencing NIRS monitoring.