Eosin Y as a direct hydrogen-atom transfer photocatalyst for the C3-H acylation of quinoxalin-2(1H)-ones. (30th March 2021)

• Record Type: Journal Article
• Authors: Ni, Hangcheng; Li, Yu; Shi, Xingzi; Pang, Yi; Jin, Congying; Zhao, Fei
• Is Part Of: Tetrahedron letters. Volume 68(2021)
• Publication Date: 2021-03-30
• Subjects: Photocatalysis -- Hydrogen-atom transfer -- Aldehyde -- Acylation -- Quinoxalin-2(1H)-one; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2021.152915
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Visible light promoted eosin Y catalyzed selective C3-H acylation of quinoxalin-2( 1H )-ones. Neutral eosin Y as the actual hydrogen-atom transfer catalyst in a green and sustainable manner. Readily available aldehyde as the radical precursor for the generation of acyl radical. Abstract: Visible light promoted eosin Y catalyzed selective C3-H acylation of quinoxalin-2( 1H )-ones has been developed in a green and sustainable manner. In contrast to the conventional anionic eosin Y-based photoredox process, neutral eosin Y acts as the actual catalyst, which was responsible for the hydrogen-atom transfer (HAT) process to generate the acyl radical with readily available aldehydes as the radical precursor.