Injectable hydrogels for anti‐tumour treatment: a review. Issue 3 (28th October 2020)

• Record Type: Journal Article
• Authors: He, Huan; Xie, Chaoming; Lu, Xiong
• Is Part Of: Biosurface and biotribology. Volume 6:Issue 3(2020)
• Page Start: 59
• Page End: 74
• Publication Date: 2020-10-28
• Subjects: cancer -- cellular biophysics -- radiation therapy -- hyperthermia -- patient treatment -- hydrogels -- tumours; anti‐tumour treatment -- solid tumours -- loading anti‐tumour materials -- anti‐tumour injectable hydrogels -- gel‐forming mechanism -- current anti‐tumour methods -- anti‐tumour mechanism -- tumour treatments -- anti‐tumour therapy; Tribology -- Periodicals; Biomedical materials -- Periodicals; Tribology -- Congresses -- Periodicals; Biomedical materials -- Congresses -- Periodicals; Biological interfaces -- Congresses -- Periodicals; Biological interfaces; Biomedical materials; Tribology; Biocompatible Materials; Surface Properties; Materials Testing; Periodicals; Electronic journals; Periodical; Electronic journals; 610.28
• DOI: 10.1049/bsbt.2020.0020
• Languages: English
• ISSNs: 2405-4518

Abstract

Abstract : Injectable hydrogels have become the material of choice for the treatment of solid tumours based on their advantages in loading anti‐tumour materials. This study reviews the main scientific research achievements on anti‐tumour injectable hydrogels in recent years. The gel‐forming mechanism of anti‐tumour injectable hydrogels was listed, and the advantages and difficulties of each gel‐forming mechanism were summarised. In addition, several current anti‐tumour methods based on injectable hydrogels were discussed, including chemotherapy, hyperthermia‐based therapy, catalytic therapy and immune therapy, as well as the integration of diagnosis and treatment to monitor the progress of cancer treatment. The anti‐tumour mechanism and the advantages and disadvantages of various tumour treatments were analysed. Finally, the future development trend of injectable hydrogels for anti‐tumour therapy was discussed.