Using genetic information to select treatment for patients with heart failure: has the time come?. (July 2009)

• Record Type: Journal Article
• Authors: Fiuzat, Mona; Felker, G Michael; Donahue, Mark P; O''Connor, Christopher M
• Is Part Of: Personalized medicine. Volume 6:Number 4(2009)
• Page Start: 385
• Page End: 392
• Publication Date: 2009-07
• Subjects: heart failure -- personalized medicine -- pharmacogenetics -- polymorphisms; Pharmacogenomics -- Periodicals; Pharmacogenetics -- Periodicals; 615.19
• DOI: 10.2217/pme.09.19
• Languages: English
• ISSNs: 1741-0541

Abstract

Personalized medicine is the concept of patient care becoming individualized based on distinctive characteristics. Pharmacogenetics is an application of personalized medicine, which may allow us to predict response to treatment based on an individual''s genetic makeup. While several therapeutic areas have made significant advances in using pharmacogenetics to tailor therapies, it is not yet widely used in the treatment of heart failure. In this review, we summarize some of the emerging data on the use of pharmacogenetics in heart failure therapies.