Focal cortical dysplasia resulting in seizures in an adult dog. Issue 1 (21st December 2015)

• Record Type: Journal Article
• Authors: Cooper, Camilla Jayne; McConnell, Fraser; Walmsley, Gemma; Gonçalves, Rita
• Is Part Of: Veterinary record case reports. Volume 3:Issue 1(2015)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2015-12-21
• Subjects: Seizures -- MRI -- cortical dysplasia -- dog; Veterinary medicine -- Case studies -- Periodicals; Veterinary medicine -- Periodicals; 636.08905
• DOI: 10.1136/vetreccr-2015-000254
• Languages: English
• ISSNs: 2052-6121

Abstract

Abstract : A two‐year‐old, neutered male, old English sheepdog was presented for further investigation of generalised tonic‐clonic seizures. MRI of the brain revealed cortical grey matter thickening, grey‐white matter blurring and malformation of the prorean and precruciate gyrus and absence of the presylvian sulcus. These findings are consistent with congenital focal cortical dysplasia; although the histopathological findings have been previously described in dogs, the MRI findings have not yet been reported in the veterinary literature. Phenobarbitone was added at the time of diagnosis with levetiracetam being added after 12 months due to worsening seizure frequency. Cortical dysplasia, although uncommon, should be considered as a differential diagnosis in an adult dog with generalised seizures.