Electrochemotherapy as treatment for generalised squamous cell carcinoma in a dog. Issue 1 (25th February 2019)

• Record Type: Journal Article
• Authors: Boncea, Ana Maria; Cristea, Anca; Bourdeau, Patrick
• Is Part Of: Veterinary record case reports. Volume 7:Issue 1(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-25
• Subjects: electrochemotherapy -- dogs -- squamous cell carcinoma -- electroporation -- cisplatin -- tumours; Veterinary medicine -- Case studies -- Periodicals; Veterinary medicine -- Periodicals; 636.08905
• DOI: 10.1136/vetreccr-2018-000787
• Languages: English
• ISSNs: 2052-6121

Abstract

Abstract : Canine squamous cell carcinoma (cSCC) is the second most common cutaneous neoplasm in dogs. Treatment options are limited. Electrochemotherapy (ECT) has been proposed as an alternative treatment for many types of tumours. To describe the use of ECT as treatment for generalised cSCC. An adult dog (four years old) was diagnosed with generalised cSCC. There were 24 tumours with the size range of 0.3–3 cm. The biopsy revealed an infiltrate rich in epithelial squamous cells, associated with pyogranulomatous inflammation. ECT was elected as treatment of choice. Cisplatin was injected intratumorously. After five minutes, the electric pulses were applied. The complete tumour regression was noted four weeks after. The dog was still in complete remission, 20 months later. This is the first case reporting a complete long‐term remission using ECT for generalised cSCC.