GENIPSO: a French prospective study assessing instantaneous prevalence, clinical features and impact on quality of life of genital psoriasis among patients consulting for psoriasis. (1st November 2018)

• Record Type: Journal Article
• Authors: Larsabal, M.; Ly, S.; Sbidian, E.; Moyal‐Barracco, M.; Dauendorffer, J.‐N.; Dupin, N.; Richard, M.A.; Chosidow, O.; Beylot‐Barry, M.
• Other Names: Abdo Ivana investigator.; Acquitter Marie investigator.; de la Breteque Mignot Maud Ami investigator.; Amici Jean‐Michel investigator.; Archier Elodie investigator.; Aubin François investigator.; Barthelemy Hugues investigator.; Baubion Emilie investigator.; Beneton Nathalie investigator.; Bolac Cécile investigator.; Bouilly Danielle investigator.; Bourseau‐Quetier Catherine investigator.; Brenaut Emilie investigator.; Buzenet Christel investigator.; Camus Magalie investigator.; Celerier Philippe investigator.; Chabbert Cécile investigator.; Chamaillard Mélanie investigator.; Charles Sophie investigator.; Darrigade Anne‐Sophie investigator.; Delarue Michele‐Pillette investigator.; Depaire Florence investigator.; Devaux Suzanne investigator.; Do‐Pham Giao investigator.; Duval‐Modeste Anne‐Benedicte investigator.; Fabre Françoise investigator.; Fauconneau Antoine investigator.; Fite Charlotte investigator.; Fleuret Camille investigator.; Girard Céline investigator.; Grande Sophie investigator.; Guillet Stéphanie investigator.; Hacard Florence investigator.; Hegazy Salama investigator.; Hosteing Stéphanie investigator.; Jacquin Marie‐Agnès investigator.; Jegou Marie‐Hélène investigator.; Joly Pascal investigator.; Jouary Thomas investigator.; Julien Denis investigator.; Kemula Mathilde investigator.; Kostrzewa Elise investigator.; Lacour Jean‐Philippe investigator.; Legrain Valérie investigator.; Livideanu Cristina investigator.; Lu Devy investigator.; Maccari François investigator.; Magne Françoise investigator.; Martin Clemmie investigator.; Meunier Laurent investigator.; Misery Laurent investigator.; Parier Josiane investigator.; Pelletier Fabien investigator.; Perrussel Marc investigator.; Petit‐Fauconneau Antoine investigator.; Peyrot Itzia investigator.; Plantin Patrice investigator.; Pruvost‐Balland Christelle investigator.; Regnier Elodie investigator.; Reynier‐Rezzi Judith investigator.; Salzes Camille investigator.; Seneschal Julien investigator.; Shollhammer Martine investigator.; Souteyrand Agathe investigator.; Staumont Delphine investigator.; Toulemonde Anne investigator.; Vanhaecke Clelia investigator.; Vedie Anne‐Laure investigator.; Versapuech Julie investigator.; Vigan Martine investigator.; Viguier Manuelle investigator.; Villani Axel investigator.;
• Is Part Of: British journal of dermatology. Volume 180:Number 3(2019)
• Page Start: 647
• Page End: 656
• Publication Date: 2018-11-01
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.17147
• Languages: English
• ISSNs: 0007-0963

Abstract

Summary: Background: Genital psoriasis is often under‐recognized. Objectives: To assess the instantaneous prevalence of genital psoriasis and describe its clinical features, association with a particular subtype of psoriasis and its impact on general and sexual quality of life (QoL). Methods: GENIPSO is a prospective study conducted by private and hospital‐based dermatologists. This study featured the consecutive inclusion of patients consulting for extragenital psoriasis. The clinical features of psoriasis and genital psoriasis were recorded and QoL and sexual health questionnaires were distributed to patients. Results: Overall, 335 of 776 patients (43·2%) included in the study had genital involvement. All were aware that they had genital lesions but only 135 patients (40%) declared that they had been previously examined. Genital lesions were associated with male sex, severity of psoriasis, age of onset > 20 years, inverse psoriasis and involvement of scalp, nail and external auditory canal, but were not associated with obesity, psoriatic arthritis and active sex life. Itching was the main symptom. Genital psoriasis was associated with impairment of QoL and sexual health according to the Dermatology Life Quality Index and the Female Sexual Function Index. Conclusions: Genital psoriasis has a high prevalence in patients consulting for extragenital psoriasis, which affects QoL, and should be taken into account by dermatologists in order to optimize global care. Abstract : What's already known about this topic? Genital psoriasis is frequent but under‐recognized. What does this study add? The instantaneous prevalence of genital psoriasis in patients consulting for extragenital psoriasis was 43·2%. All patients were aware of their genital psoriasis but only 40% declared having had a previous examination of the genital area by a dermatologist. What are the clinical implications of this work? Owing to its frequency and impact on general and sexual quality of life, genital psoriasis should be screened in all patients, including those already receiving treatment for psoriasis. Respond to this article Linked Comment: Ryan. Br J Dermatol 2019; 180 :460–461. Plain language summary available online