Design of binary subtractor using actin quantum cellular automata. Issue 1 (13th November 2017)

• Record Type: Journal Article
• Authors: Sadhu, Tapatosh; Das, Biplab; De, Debashis; Das, Jadav Chandra
• Is Part Of: IET nanobiotechnology. Volume 12:Issue 1(2018)
• Page Start: 32
• Page End: 39
• Publication Date: 2017-11-13
• Subjects: cellular automata -- molecular biophysics -- molecular configurations -- biology computing -- proteins -- logic circuits -- biomolecular electronics -- cellular biophysics -- fault tolerance; binary subtractor -- actin quantum cellular automata -- biological protein -- cellular structure -- cytoskeletal signalling events -- intracellular signalling events -- actin filaments -- logic subtractor circuits -- binary bits -- logic design -- half binary subtractors -- full binary subtractors -- optimised results -- single automata block -- Simulink -- design approaches -- reliability -- fault‐tolerance check -- circuit size -- circuit efficiency -- unconventional computing -- nanoscale biomolecular networks -- cost‐effective biomolecular networks; Biotechnology -- Periodicals; Nanotechnology -- Periodicals; 660.6
• DOI: 10.1049/iet-nbt.2017.0149
• Languages: English
• ISSNs: 1751-8741

Abstract

Abstract : Actin is a biological protein that provides support to the cellular structure and plays a crucial role in cytoskeletal and intra‐cellular signalling events. Logic circuits can be designed with actin filaments with the help of actin quantum automata. The authors use a rule (4, 27) to implement some novel designs of logic subtractor circuits on this automata to achieve the difference in two binary bits. Logic design of both half and full binary subtractors is proposed in this study. Actin‐based quantum cellular automata can be used in different combinations of input to get optimised results from the circuits. The authors focus on consolidating the designs inside single automata block to generate output in a less number of timesteps and less overheads. The designs are simulated with Simulink and this way output is verified for these different design approaches. Reliability and fault‐tolerance check is another interesting part of this study. To get a better idea of the optimisation achieved, the authors have also presented a comparative study between the proposed designs in terms of circuit size and efficiency. With all these parameters involved, this study explores opportunities for future implementation of unconventional computing in nano‐scale and cost‐effective bio‐molecular networks.