Evaluation of the effect of time on the distribution of zinc oxide nanoparticles in tissues of rats and mice: a systematic review. Issue 3 (1st June 2016)

• Record Type: Journal Article
• Authors: Chen, Aijie; Feng, Xiaoli; Sun, Ting; Zhang, Yanli; An, Shengli; Shao, Longquan
• Is Part Of: IET nanobiotechnology. Volume 10:Issue 3(2016)
• Page Start: 97
• Page End: 106
• Publication Date: 2016-06-01
• Subjects: nanoparticles -- zinc compounds -- II‐VI semiconductors -- wide band gap semiconductors -- biological tissues -- lung -- liver -- brain -- kidney -- toxicology -- biology computing; time effect -- zinc oxide nanoparticles distribution -- rat tissues -- mice tissues -- PubMed -- Embase -- SpringerLink -- Scopus -- Science Direct -- Cochrane -- CNKI -- Wanfang -- vip databases -- screening -- data extraction -- quality assessment -- Zn content -- liver -- kidney -- lung -- brain -- time 24 h -- ZnO; Biotechnology -- Periodicals; Nanotechnology -- Periodicals; 660.6
• DOI: 10.1049/iet-nbt.2015.0006
• Languages: English
• ISSNs: 1751-8741

Abstract

Abstract : To evaluate the time effect on the distribution of zinc oxide nanoparticles (ZnO NPs) in tissues from rats and mice, a search on the PubMed, Embase, SpringerLink, Scopus, Science Direct, Cochrane, CNKI, Wanfang, and vip databases up to September 2014 was performed, followed by screening, data extraction, and quality assessment. Thirteen studies were included. At 24 h, Zn content was mainly distributed in the liver, kidney, and lung. At ≥7 days, Zn content was mainly distributed in the liver, kidney, lung, and brain. ZnO NPs are readily deposited in tissues. Furthermore, as time increases, Zn content decreases in the liver and kidney, but increases in the brain.