Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella foenum‐graecum seed extract. Issue 4 (23rd March 2018)

• Record Type: Journal Article
• Authors: Goyal, Shivangi; Gupta, Nidhi; Kumar, Ajeet; Chatterjee, Sreemoyee; Nimesh, Surendra
• Is Part Of: IET nanobiotechnology. Volume 12:Issue 4(2018)
• Page Start: 526
• Page End: 533
• Publication Date: 2018-03-23
• Subjects: antibacterial activity -- cancer -- biomedical materials -- silver -- nanofabrication -- nanomedicine -- nanoparticles -- microorganisms -- skin -- cellular biophysics -- biochemistry -- light scattering -- X‐ray chemical analysis -- X‐ray diffraction -- Fourier transform infrared spectra -- particle size; antibacterial potential -- anticancer potential -- antioxidant potential -- silver nanoparticles -- Trigonella foenum‐graecum seed extract -- eco‐friendly method -- biosynthesis -- reaction time -- AgNO3 concentration -- TFG extract amount -- physicochemical characterisation -- dynamic light scattering -- field emission electron microscopy -- energy dispersive X‐ray spectroscopy -- X‐ray diffraction -- Fourier transform infrared spectroscopy -- size determination -- TFG‐AgNPs size -- Escherichia coli -- Proteus vulgaris -- Pseudomonas aeruginosa -- Staphylococcus aureus -- skin cancer cell line A431 -- Ag; Biotechnology -- Periodicals; Nanotechnology -- Periodicals; 660.6
• DOI: 10.1049/iet-nbt.2017.0089
• Languages: English
• ISSNs: 1751-8741

Abstract

Abstract : In this study, the authors report a simple and eco‐friendly method for the synthesis of silver nanoparticles (AgNPs) using Trigonella foenum‐graecum (TFG) seed extract. They explored several parameters dictating the biosynthesis of TFG‐AgNPs such as reaction time, temperature, concentration of AgNO3, and TFG extract amount. Physicochemical characterisation of TFG‐AgNPs was done on dynamic light scattering (DLS), field emission electron microscopy, energy dispersive X‐ray spectroscopy, X‐ray diffraction and Fourier transform infrared spectroscopy. The size determination studies using DLS revealed of TFG‐AgNPs size between 95 and 110 nm. The antibacterial activity was studied against Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus. The biosynthesised TFG‐AgNPs showed remarkable anticancer efficacy against skin cancer cell line, A431 and also exhibited significant antioxidant efficacy.