A Hungry Bone Syndrome Predicted by 18F-Fluorocholine PET/CT. (November 2019)

• Record Type: Journal Article
• Authors: Paepegaey, Anne-Cécile; Velayoudom, Fritz-Line; Housni, Selma; Gauthé, Mathieu; Groussin, Lionel
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 11(2019)
• Publication Date: 2019-11
• Subjects: 18F-fluorocholine PET/CT -- hungry bone syndrome -- hyperparathyroidism; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002676
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Predicting hungry bone syndrome (HBS) after surgical cure of primary hyperparathyroidism (PHPT) can be challenging. A 57-year-old man diagnosed with PHPT was assessed preoperatively by 18 F-fluorocholine PET/CT. An intense and diffuse tracer uptake of the axial and peripheral skeleton was visualized, in addition to a pathologic uptake suggestive of hyperfunctioning parathyroid gland. After the removal of a parathyroid adenoma, a severe and prolonged HBS requiring high doses of calcium and active metabolites of vitamin D was observed. This observation suggests that intense and diffuse bone uptake on 18 F-fluorocholine PET/CT could be a predictive factor for HBS in patients with PHPT.