Major Issues of Care in Thalassemia Major Children Refugees. Issue 8 (November 2019)

• Record Type: Journal Article
• Authors: Hamouni, Eglantine; Armari, Corinne; Dupuis, Clémentine; Giroux-Lathuile, Claudine; Petit, Audrey; Plantaz, Dominique; Adjaoud, Dalila; Rubio, Amandine
• Is Part Of: Journal of pediatric hematology/oncology. Volume 41:Issue 8(2019)
• Publication Date: 2019-11
• Subjects: thalassemia major -- alloimmunization -- hemochromatosis -- osteoporosis -- hypopituitarism; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001288
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Beta thalassemia major (βTM) is the most common inherited hemoglobinopathy. Management essentially focuses on preventing and treating complications. Conventional treatment is based on a regular blood transfusion program, and chelation therapy. Management essentially focuses on preventing and treating complications. Severe complications of βTM are very rarely seen in children in Europe. In the context of the migrant crisis, pediatricians will be confronted with the challenge of managing severe complicated βTM. We report the case of 2 Syrian 10-year-old twin girls who arrived to France with numerous and severe complications of βTM: hemochromatosis, alloimmunization, hypopituitarism, osteopenia… Their clinical management, which led to successful vital and functional improvement, is reported in this article.