Design of dynamic genetic memory. Issue 6 (1st December 2017)

• Record Type: Journal Article
• Authors: Hu, Yu‐Jia; Lin, Chun‐Liang; Li, Wei‐Xian
• Is Part Of: IET systems biology. Volume 11:Issue 6(2017)
• Page Start: 182
• Page End: 189
• Publication Date: 2017-12-01
• Subjects: DRAM chips -- genetic engineering -- biocomputers -- bioinformatics -- equivalent circuits -- RC circuits; dynamic genetic memory design -- electronic systems -- dynamic random access memory -- modern silicon computer -- biocomputer -- bioinformation -- binary logic -- logical high level -- logical low level -- normalised form -- genetic DRAM -- modified electronic configuration -- biological reaction -- equivalent RC circuit -- memory cell -- fundamental functions -- genetic toggle switch -- data hold -- biostorage module; Systems biology -- Periodicals; Cell physiology -- Periodicals; Biological systems -- Mathematical models -- Periodicals; Genetics -- Mathematical models -- Periodicals; Computational biology -- Periodicals; 573
• DOI: 10.1049/iet-syb.2017.0021
• Languages: English
• ISSNs: 1751-8849

Abstract

Abstract : In electronic systems, dynamic random access memory (DRAM) is one of the core modules in the modern silicon computer. As for a bio‐computer, one would need a mechanism for storage of bio‐information named 'data', which, in binary logic, has two levels, logical high and logical low, or in the normalised form, '1' and '0'. This study proposes a possible genetic DRAM based on the modified electronic configuration, which uses the biological reaction to fulfil an equivalent RC circuit constituting a memory cell. The authors implement fundamental functions of the genetic DRAM by incorporating a genetic toggle switch for data hold. The results of simulation verify that the basic function can be used on a bio‐storage module for the future bio‐computer.