Adaptive fractional‐order blood glucose regulator based on high‐order sliding mode observer. Issue 2 (5th March 2019)

• Record Type: Journal Article
• Authors: Delavari, Hadi; Heydarinejad, Hamid; Baleanu, Dumitru
• Is Part Of: IET systems biology. Volume 13:Issue 2(2019)
• Page Start: 43
• Page End: 54
• Publication Date: 2019-03-05
• Subjects: variable structure systems -- biochemistry -- blood -- robust control -- medical control systems -- observers -- sugar -- diseases -- calculus -- adaptive control -- cellular biophysics; fractional‐order SMC -- adaptive SMC -- fractional calculus -- robust performance -- adaptive fractional‐order blood glucose regulator -- insulin‐producing beta‐cells -- exogenous insulin administration -- diabetes patients -- Bergman minimal model -- mode control -- blood glucose regulation -- pancreas -- type I diabetes -- state estimation -- high‐order sliding mode observer -- sliding mode control -- degree of freedom -- numerical simulation; Systems biology -- Periodicals; Cell physiology -- Periodicals; Biological systems -- Mathematical models -- Periodicals; Genetics -- Mathematical models -- Periodicals; Computational biology -- Periodicals; 573
• DOI: 10.1049/iet-syb.2018.5016
• Languages: English
• ISSNs: 1751-8849

Abstract

Abstract : Type I diabetes is described by the destruction of the insulin‐producing beta‐cells in the pancreas. Hence, exogenous insulin administration is necessary for Type I diabetes patients. In this study, to estimate the states that are not directly available from the Bergman minimal model a high‐order sliding mode observer is proposed. Then fractional calculus is combined with sliding mode control (SMC) for blood glucose regulation to create more robustness performance and make more degree of freedom and flexibility for the proposed method. Then an adaptive fractional‐order SMC is proposed. The adaptive SMC protect controller against disturbance and uncertainties while the fractional calculus provides robust performance. Numerical simulation verifies that the proposed controllers have better performance in the presence of disturbance and uncertainties without chattering.