CMOS‐based implantable glucose monitoring device with improved performance and reduced invasiveness. Issue 10 (1st May 2015)

• Record Type: Journal Article
• Authors: Kawamura, T.; Masuda, K.; Hirai, T.; Ohta, Y.; Motoyama, M.; Takehara, H.; Noda, T.; Sasagawa, K.; Tokuda, T.; Okitsu, T.; Takeuchi, S.; Ohta, J.
• Is Part Of: Electronics letters. Volume 51:Issue 10(2015)
• Page Start: 738
• Page End: 740
• Publication Date: 2015-05-01
• Subjects: CMOS integrated circuits -- patient monitoring -- sugar -- blood -- biomedical equipment -- fluorescence -- hydrogels -- needles -- diseases -- CMOS image sensors; CMOS‐based implantable glucose monitoring device -- implantable glucose monitoring device -- CMOS line sensor -- glucose‐responsive fluorescent hydrogel -- proof‐of‐concept device -- injectable device diameter -- commercially available 16‐gauge syringe needle -- sensor performance; Electronics -- Periodicals; 621.381
• DOI: 10.1049/el.2015.0612
• Languages: English
• ISSNs: 0013-5194

Abstract

Abstract : An implantable glucose monitoring device based on a CMOS line sensor combined with a glucose‐responsive fluorescent hydrogel is developed. An implantable glucose monitoring device with sufficient sensitivity and response time is realised, which is an improvement over the authors' previous proof‐of‐concept device. A reduction of the sensor size made the device diameter injectable with a commercially available 16‐gauge syringe needle. The sensor's performance was confirmed through both in vitro and in vivo experiments.