Two Fatty Liver Conditions Masquerading as Autoimmune Hepatitis. (9th March 2021)

• Record Type: Journal Article
• Authors: Hendrie, Jonathan David; Blumer, Mary Crouse; Fenton, Hubert Henry; Abrams, Gary Anthony
• Other Names: Komatsu Haruki Academic Editor.
• Is Part Of: Case reports in hepatology. Volume 2021(2021)
• Publication Date: 2021-03-09
• Subjects: Liver -- Periodicals; Liver -- Diseases -- Periodicals; Liver Diseases; Liver; Liver; Liver -- Diseases; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.36
• DOI: 10.1155/2021/8820350
• Languages: English
• ISSNs: 2090-6587

Abstract

Abstract : Acute fatty liver of pregnancy (AFLP) is a rare obstetric condition that classically presents in the third trimester or early postpartum period and can lead to liver failure and death. Only six second trimester AFLP cases have been reported in the English literature. We present the earliest case of AFLP at 15 weeks of gestation confounded by a high titer anti-nuclear antibody (ANA >1 : 1280) and concern for autoimmune hepatitis. Our patient had intrauterine fetal demise with prompt dilation and evacuation. Sepsis and multisystem organ failure ensued, and she was transferred to a liver transplant center where she expired without further intervention.