OXTR rs53576 polymorphism impacts interpersonal adaptability: Dispositional forgiveness as a mediator. (May 2019)

• Record Type: Journal Article
• Authors: Zhao, Jing; Yang, Yafang; Li, Xiaohan; Zheng, Linfeng; Xue, Mengying; Zhang, Mengfei; Wang, Chunlan; Yu, Rongjun; Gong, Pingyuan
• Is Part Of: Psychoneuroendocrinology. Volume 103(2019)
• Page Start: 8
• Page End: 13
• Publication Date: 2019-05
• Subjects: Oxytocin receptor gene -- Polymorphism -- Interpersonal adaptability -- Empathic perception -- Forgiveness; Psychoneuroendocrinology -- Periodicals; Endocrinology -- Periodicals; Neurology -- Periodicals; Psychiatry -- Periodicals; Neuropsychoendocrinologie -- Périodiques; 616.8
• DOI: 10.1016/j.psyneuen.2018.12.240
• Languages: English
• ISSNs: 0306-4530

Abstract

Highlights: The G alleles of OXTR rs53576 is related to high interpersonal adaptability. The G alleles of OXTR rs53576 is related to high dispositional forgiveness. Dispositional forgiveness mediates the association of OXTR rs53576 with interpersonal adaptability. Abstract: Polymorphisms in the oxytocin receptor ( OXTR ) gene have been shown to be related to individual differences in social skills that are important for building and maintaining social relationships, such as the capability to efficiently process social information and regulate emotions. However, what remains unclear is the potential roles of OXTR polymorphisms in interpersonal adaptability, namely the ability to cope with the situational demands of interpersonal interactions. In this study, we examined the roles of OXTR rs53576 polymorphism in interpersonal adaptability, empathic perception, and dispositional forgiveness in a cohort of 573 college freshmen. The results indicated that the scores on interpersonal adaptability and dispositional forgiveness, apart from empathic perception, increased as functions of the number of G alleles of OXTR rs53576. Moreover, dispositional forgiveness, but not empathic perception, mediated the association between OXTR rs53576 and interpersonal adaptability. The findings highlight the influences of the OXTR gene on adaptive interpersonal interactions, especially when individuals face changing social situations.