Rh(III)-catalyzed [4 + 1]-annulation of azobenzenes with α- carbonyl sulfoxonium ylides toward 3-acyl-(2H)-indazoles. Issue 23 (6th June 2018)

• Record Type: Journal Article
• Authors: Zhu, Jiawei; Sun, Song; Cheng, Jiang
• Is Part Of: Tetrahedron letters. Volume 59:Issue 23(2018)
• Page Start: 2284
• Page End: 2287
• Publication Date: 2018-06-06
• Subjects: Rhodium-catalyzed -- Sulfoxonium ylides -- 2H-indazoles; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.05.001
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Annulation of azobenzenes with α- carbonyl sulfoxonium ylides. Features with excellent yields and good functional group compatibilities. Sulfoxonium ylides served as efficient and stable carbene precursor. Abstract: A Rh(III)-catalyzed [4 + 1]-annulation of azobenzenes with α - carbonyl sulfoxonium ylides was developed to access 2 H -indazoles in moderate to excellent yields with good functional group compatibilities. It proceeded with the sequential insertion of the Rh(III) carbene to the C−H bond and cyclization steps, where sulfoxonium ylides served as efficient and stable carbene precursor.