Medical approach to advanced prostate cancer in older patients. (October 2008)

• Record Type: Journal Article
• Authors: Falci, C; Brunello, A; Basso, U; Roma, A; Monfardini, S
• Is Part Of: Aging health. Volume 4:Number 5(2008)
• Page Start: 481
• Page End: 494
• Publication Date: 2008-10
• Subjects: androgen ablation -- chemotherapy -- elderly; Geriatrics -- Periodicals; 618.97005
• DOI: 10.2217/1745509X.4.5.481
• Languages: English
• ISSNs: 1745-509X

Abstract

Prostate cancer is largely a disease of older men, with more than 90% of mortality observed in patients over 65 years. In the metastatic setting, a number of treatment options are available, with androgen-deprivation therapy being the first-choice, but few studies have examined the feasibility and efficacy of endocrine therapy and chemotherapy in men aged 70 years or older. Since the preservation of quality of life is the main objective of treatment in metastatic prostate cancer, every therapeutic decision should be conditioned by results of a geriatric comprehensive assessment.