Multimodality treatment of two cases of intracardiac leiomyomatosis with enormous mass in the abdominopelvic cavity. Issue 2 (February 2013)

• Record Type: Journal Article
• Authors: Zhang, Yong; Zhu, Jun; Wang, Chunsheng; Tu, Ruiqin; Jiang, Junhao; Lu, Weiqi
• Is Part Of: Expert review of anticancer therapy. Volume 13:Issue 2(2013)
• Page Start: 137
• Page End: 141
• Publication Date: 2013-02
• Subjects: intravenous leiomyomatosis -- intracardiac leiomyomatosis -- multimodality therapy; Cancer -- Treatment -- Periodicals; 616.99406
• DOI: 10.1586/era.12.145
• Languages: English
• ISSNs: 1473-7140

Abstract

Difficulties in the preoperative preparation and surgical management of patients with intravenous leiomyomatosis involving the heart and pulmonary artery resulting in intracardiac leiomyomatosis necessitate further investigation of this condition. In this report, we describe the interdisciplinary treatment of two cases of intracardiac leiomyomatosis with enormous mass in the abdominopelvic cavity. A single-stage surgical procedure with a combined thoracic and abdominal approach was performed in both cases and the tumors were successfully excised. The procedure also involved removal of the atrial, caval and other venular extensions, and total hysterectomy with bilateral salpingo-oophorectomy. Postoperative pathology findings confirmed the diagnosis of intravenous leiomyomatosis. Neither patient died perioperatively, and no complications were observed.