Anticoagulation treatment. (April 2021)

• Record Type: Journal Article
• Authors: Breen, Karen A.
• Is Part Of: Medicine. Volume 49:Number 4(2021)
• Page Start: 234
• Page End: 237
• Publication Date: 2021-04
• Subjects: Anticoagulant monitoring -- heparin -- MRCP -- reversal of anticoagulation -- warfarin; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Médecine factuelle -- Périodiques; Medicine; Periodicals; Electronic journals; Electronic journals; 610
• DOI: 10.1016/j.mpmed.2021.01.011
• Languages: English
• ISSNs: 1357-3039

Abstract

Abstract: Anticoagulant therapy using heparins and vitamin K antagonists has been used effectively for the prevention and treatment of thromboembolic events for many years. However, therapy is associated with a significant risk of haemorrhagic complications, warranting careful consideration of the need for anticoagulation. Recognized drawbacks of current anticoagulants are their unpredictable pharmacokinetics and the need for laboratory monitoring, which have led in recent years to the development of direct oral anticoagulant agents.