Comparison of the OI and PaO2/FiO2 score in evaluating PARDS requiring mechanical ventilation. Issue 5 (14th December 2020)

• Record Type: Journal Article
• Authors: Shen, Huili; Qu, Dong; Na, Weilan; Liu, Shuang; Huang, Siyuan; Hui, Yi
• Is Part Of: Pediatric pulmonology. Volume 56:Issue 5(2021)
• Page Start: 1182
• Page End: 1188
• Publication Date: 2020-12-14
• Subjects: arterial partial pressure of oxygen to the fraction of inspired oxygen (PaO2/FiO2 -- oxygenation index (OI) -- P/F) -- pediatric acute respiratory distress syndrome (PARDS); Pediatric respiratory diseases -- Periodicals; Pediatrics -- Periodicals; 618.922
• DOI: 10.1002/ppul.25194
• Languages: English
• ISSNs: 8755-6863

Abstract

Abstract: Aim: To examine the differences between oxygenation index (OI) and arterial partial pressure of oxygen to the fraction of inspired oxygen (PaO2 /FiO2, [P/F]) in evaluating the severity of pediatric acute respiratory distress syndrome (PARDS). Methods: The severity of PARDS was graded by using the OI score and P/F ratio, respectively. The data including clinical indexes and prognosis indicators were recorded and analyzed. Results: During the 3‐year study period, there were significant differences between OI and P/F scores in the severity grading of PARDS patients ( p < .05). However, in severe diseases, both the scorings of OI and P/F were consistent (24.6% vs. 25.6%). The OI scores appeared more accurate when compared with P/F in the correlation between them and the pediatric critical illness score, multiple organ dysfunction syndromes (MODS), pressure indexes of ventilators and patients' prognosis. In the receiver operating characteristic curve, the critical values of OI and P/F were 8.42 and 144.71. Area under the curve of them were 0.839 and 0.853. The sensitivity values were both 0.854. The specificity values were 0.584 and 0.602. Conclusions: The OI and P/F were consistent in designating patients with severe PARDS. Among patients with mild to moderate diseases, the P/F could still be used for rapid determination given its simple calculation. Combined with the prognostic factors, the OI score was more accurate.