Temperature and pH Responsive Light‐Harvesting System Based on AIE‐Active Microgel for Cell Imaging. Issue 7 (4th February 2021)

• Record Type: Journal Article
• Authors: Fan, Xiaotong; Teng, Choon Peng; Yeo, Jayven Chee Chuan; Li, Zibiao; Wang, Tingting; Chen, Haiming; Jiang, Lu; Hou, Xunan; He, Chaobin; Liu, Junqiu
• Is Part Of: Macromolecular rapid communications. Volume 42:Issue 7(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-02-04
• Subjects: aggregation‐induced emission -- fluorescence -- light harvesting systems -- microgels -- temperature -- pH responsive materials; Macromolecules -- Periodicals; Polymers -- Periodicals; Chemistry -- Periodicals; 547.705
• DOI: 10.1002/marc.202000716
• Languages: English
• ISSNs: 1022-1336

Abstract

Abstract: A highly emissive microgel is synthesized by polymerizing tetraphenylethene (TPE) based comonomers, acrylic acid, NIPAM, and permanent crosslinker ethylenebisacrylamide (BIS) (named as TPE microgel), which exhibited temperature responsive fluorescence emission. Rhodamine B (RhB), a positively charged molecule, is then inserted onto the surface of fabricated microgels through electrostatic interaction. As a result, a novel artificial light harvesting system with high energy transfer efficiency is constructed (named as TPE microgel‐RhB light harvesting system), which is the first light harvesting system based on TPE microgels presenting dual response to pH and temperature. MTT assay indicates the fabricated TPE microgel and TPE microgel‐RhB light harvesting system has good cytocompatibility. The strong fluorescence and good cytocompatibility make them perfect candidates for cell imaging. The prepared emissive microgel and light‐harvesting system with desirable fluorescent property not only provide a new strategy for the fabrication of tunable luminescent nanomaterials, but also expand potential applications in the fields of stomach recognition, temperature sensors, and drug delivery. Abstract : A highly emissive microgel containing AIEgens is successfully fabricated, which presents temperature responsive fluorescence intensity. Rhodamine B (RhB), the positively charged molecule, is incorporated onto the fabricated microgels through electrostatic interaction. As a result, an artificial light harvesting system presenting dual response to pH and temperature is innovatively constructed, which can be used for cell imaging.