Experimental therapies under investigation for COVID-19. Issue 2 (4th March 2021)

• Record Type: Journal Article
• Authors: Golamari, Reshma; Kapoor, Neeru; Devaraj, Tanuja; Sahu, Nitasa; Kramer, Courtney; Jain, Rohit
• Is Part Of: Journal of community hospital internal medicine perspectives. Volume 11:Issue 2(2021)
• Page Start: 187
• Page End: 193
• Publication Date: 2021-03-04
• Subjects: COVID-19 treatment -- therapies for COVID-19 -- pandemic drugs -- remdesivir -- hydroxychloroquine; Internal medicine -- Periodicals; Hospitals -- Periodicals; Hospitals, Community; Internal Medicine; Hospitals; Internal medicine; Periodicals; Periodicals; 610
• DOI: 10.1080/20009666.2021.1874093
• Languages: English
• ISSNs: 2000-9666

Abstract

ABSTRACT: Coronavirus Disease 2019, caused by the virus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is a pandemic first discovered in Wuhan, China which has claimed over 1.7 million lives to date across the globe as of 24 December 2020. As the virus spreads across the world affecting millions of patients, there has been a massive movement to discover readily available and effective treatment options including vaccines. One of the limiting factors in treating the disease is its varied presentation and effect in patients, ranging from asymptomatic patients to those left in intensive care units, intubated and fighting for their lives. There are numerous clinical trials and small-scale studies underway to investigate potential treatment options. However, very few studies and drugs demonstrated efficacy while many more are under investigation, leaving care teams dependent on supportive care coupled with experimental treatment options. In this review, we summarize the various treatment options explored to treat COVID-19, discussing possible the mechanisms of fighting the virus.