A Positive Feedback Loop Governed by SUB1A1 Interaction with MITOGEN-ACTIVATED PROTEIN KINASE3 Imparts Submergence Tolerance in Rice. Issue 5 (14th April 2016)

• Record Type: Journal Article
• Authors: Singh, Pallavi; Sinha, Alok Krishna
• Is Part Of: The Plant Cell. Volume 28:Issue 5(2016)
• Page Start: 1127
• Page End: 1143
• Publication Date: 2016-04-14
• DOI: 10.1105/tpc.15.01001
• Languages: English
• ISSNs: 1040-4651

Abstract

Abstract : Under inundation of rice, the SUB1A1 gene is subject to posttranslational regulation by a mitogen-activated protein kinase, MPK3. Abstract: Mitogen-activated protein kinase (MAPK ) signal transduction networks have been extensively explored in plants; however, the connection between MAPK signaling cascades and submergence tolerance is currently unknown. The ethylene response factor-like protein SUB1A orchestrates a plethora of responses during submergence stress tolerance in rice ( Oryza sativa ). In this study, we report that MPK3 is activated by submergence in a SUB1A-dependent manner. MPK3 physically interacts with and phosphorylates SUB1A in a tolerant-allele-specific manner. Furthermore, the tolerant allele SUB1A1 binds to the MPK3 promoter and regulates its expression in a positive regulatory loop during submergence stress signaling. We present molecular and physiological evidence for the key role of the MPK3-SUB1A1 module in acclimation of rice seedlings to the adverse effects of submergence. Overall, the results provide a mechanistic understanding of submergence tolerance in rice.