Does Exposure of Smart Phones during Pregnancy Affect the Offspring's Ovarian Reserve? A Rat Model Study. (15th April 2021)

• Record Type: Journal Article
• Authors: Calis, Pinar; Seymen, Merve; Soykan, Yagmur; Delen, Kevser; Aral, Bahriye Sirav; Take Kaplanoglu, Gulnur; Karcaaltincaba, Deniz
• Is Part Of: Fetal and pediatric pathology. Volume 40:Number 2(2021)
• Page Start: 142
• Page End: 152
• Publication Date: 2021-04-15
• Subjects: Radiofrequency radiation -- smartphones -- pregnancy -- ovarian reserve; Pathology, Molecular -- Periodicals; Pediatrics -- Periodicals; Molecular biology -- Periodicals; Pediatric pathology -- Periodicals; Fetal Diseases -- pathology -- Periodicals; Infant, Newborn, Diseases -- pathology -- Periodicals; Pediatrics -- Periodicals; 618.92007
• DOI: 10.1080/15513815.2019.1692112
• Languages: English
• ISSNs: 1551-3815

Abstract

Abstract: Objective: We investigated the effect of prenatal exposure to smart phone radiation and the protective effect of omega-3 on ovarian reserve of offspring. Methods: 24 pregnant Wistar albino rats were divided into four groups. Group-I received neither radiofrequency (RF) radiation nor omega-3, group-II received RF, group-III received RF radiation and 300 mg omega-3 and group-IV received RF radiation and 600 mg Omega-3 till birth. At 42 days, bilateral oophorectomy was performed on all female offspring for follicle count and immunohistochemical staining (GDF9, FOXO1 and TUNEL). Results: Group-II had significantly lower mean number of primordial (p = 0.006), secondary follicles(p = 0.003) and a higher atresia score. Group-III variables were comparable with group-I variables. Group-IV had statistically higher median number of atretic follicles than group-I (p = 0.023). Conclusions: Ovarian reserve of offspring diminished with RF exposure during pregnancy. Omega-3 supplementation during pregnancy may reduce the potential premature ovarian failure.