Immunological detection of serum antibodies in pediatric medical workers exposed to varying levels of SARS-CoV-2. Issue 1 (January 2021)

• Record Type: Journal Article
• Authors: Tu, Danna; Shu, Junhua; Wu, Xiaoli; Li, Heng; Xia, Zhi; Zhang, Yanfang; Fang, Yaohui; Shen, Shu; Guan, Wuxiang; Wang, Hualin; Huang, Zhaoxuan; Wang, Guirong; Zhou, Xiaoqin; Deng, Fei
• Is Part Of: Journal of infection. Volume 82:Issue 1(2021)
• Page Start: 159
• Page End: 198
• Publication Date: 2021-01
• Subjects: Infection -- Periodicals; Bacterial Infections -- Periodicals; Communicable Diseases -- Periodicals; Electronic journals; 616.905
• DOI: 10.1016/j.jinf.2020.07.023
• Languages: English
• ISSNs: 0163-4453

Abstract

Highlights: Pediatric healthcare workers are at risk for SARS-CoV-2 transmission from children and aerosols increase SARS-CoV-2 infection rate. ELISA and dual-target fluorescence accurately detect SARS-CoV-2 antibodies indicated that antibody detection should be considered as an auxiliary diagnosis of COVID-19. Antibody positive subjects tested negative for SARS-CoV-2 neutralizing antibodies and SARS-CoV-2 antibodies diminish to near undetectable levels within two months.