Evolutionary Patterns and Coevolutionary Consequences of MIRNA Genes and MicroRNA Targets Triggered by Multiple Mechanisms of Genomic Duplications in Soybean. Issue 3 (6th March 2015)

• Record Type: Journal Article
• Authors: Zhao, Meixia; Meyers, Blake C.; Cai, Chunmei; Xu, Wei; Ma, Jianxin
• Is Part Of: The Plant Cell. Volume 27:Issue 3(2015)
• Page Start: 546
• Page End: 562
• Publication Date: 2015-03-06
• DOI: 10.1105/tpc.15.00048
• Languages: English
• ISSNs: 1040-4651

Abstract

Abstract : A genome-wide analysis and interspecific comparison of MIRNA genes revealed the patterns of MIRNA gene evolution subsequent to the recent whole-genome duplication event in soybean. Abstract: The evolutionary dynamics of duplicated protein-encoding genes (PEGs ) is well documented. However, the evolutionary patterns and consequences of duplicated MIRNA s and the potential influence on the evolution of their PEG targets are poorly understood. Here, we demonstrate the evolution of plant MIRNA s subsequent to a recent whole-genome duplication. Overall, the retention of MIRNA duplicates was correlated to the retention of adjacent PEG duplicates, and the retained MIRNA duplicates exhibited a higher level of interspecific preservation of orthologs than singletons, suggesting that the retention of MIRNA duplicates is related to their functional constraints and local genomic stability. Nevertheless, duplication status, rather than local genic collinearity, was the primary determinant of levels of nucleotide divergence of MIRNA s. In addition, the retention of duplicated MIRNA s appears to be associated with the retention of their corresponding duplicated PEG targets. Furthermore, we characterized the evolutionary novelty of a legume-specific microRNA (miRNA ) family, which resulted from rounds of genomic duplication, and consequent dynamic evolution of its NB-LRR targets, an important gene family with primary roles in plant-pathogen interactions. Together, these observations depict evolutionary patterns and novelty of MIRNA s in the context of genomic duplication and evolutionary interplay between MIRNA s and their PEG targets mediated by miRNAs .