The effect of botulinum toxin-A injection into the masseter muscles on prevention of plate fracture and post-operative relapse in patients receiving orthognathic surgery. Issue 1 (December 2018)

• Record Type: Journal Article
• Authors: Shin, Sung-Ho; Kang, Yei-Jin; Kim, Seong-Gon
• Is Part Of: Maxillofacial Plastic and Reconstructive Surgery. Volume 40:Issue 1(2018)
• Page Start: 1
• Page End: 5
• Publication Date: 2018-12
• Subjects: Botulinum toxins -- Type A -- Fracture fixation -- Internal -- Osteotomy -- Sagittal split ramus -- Postoperative complications; 617.6
• DOI: 10.1186/s40902-018-0174-0
• Languages: English
• ISSNs: 2288-8586

Abstract

Abstract Background Botulinum toxin-A (BTX-A) injection into muscle reduces muscular power and may prevent post-operative complication after orthognathic surgery. The purpose of this study was (1) to evaluate BTX-A injection into the masseter muscle on the prevention of plate fracture and (2) to compare post-operative relapse between the BTX-A injection group and the no injection group. Methods Sixteen patients were included in this study. Eight patients received BTX-A injection bilaterally, and eight patients served as control. All patients received bilateral sagittal split ramus osteotomy for the mandibular setback and additional surgery, such as LeFort I osteotomy or genioplasty. Post-operative plate fracture was recorded. SNB angle, mandibular plane angle, and gonial angle were used for post-operative relapse. Results Total number of fractured plates in patients was 2 out of 16 plates in the BTX-A injection group and that was 8 out of 16 plates in the no treatment group (P = 0.031). However, there were no significant differences in post-operative changes in SNB angle, mandibular plane angle, and gonial angle between groups (P > 0.05). Conclusions BTX-A injection into the masseter muscle could reduce the incidence of plate fracture.