Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales. (6th January 2018)

• Record Type: Journal Article
• Authors: Grierson, Sylvia S; Werling, Dirk; Bidewell, Cornelia; Williamson, Susanna
• Is Part Of: Veterinary record. Volume 182:Number 1(2018)
• Page Start: 22
• Page End: 22
• Publication Date: 2018-01-06
• Subjects: Pigs -- Virology -- Porcine Circovirus; Veterinary medicine -- Periodicals; Médecine vétérinaire -- Périodiques; Veterinary medicine; Veterinary Medicine; Periodicals; Periodical; Electronic journals; 636.089
• DOI: 10.1136/vr.104450
• Languages: English
• ISSNs: 0042-4900

Abstract

Abstract : Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed. The authors carried out a genotyping study to characterise PCV2 associated with confirmed PCVD cases in England and Wales from 2011 to January 2016 (n=65). A partial fragment of PCV2 genome encompassing ORF2 was amplified and sequenced from 45 cases of PCVD. The majority of sequences were genotype PCV2b but four sequences were PCV2d. The significance of the emergence of PCV2d in England and elsewhere in the world is not yet known, although it does appear to represent an ongoing global genotype shift.