Design and characterization of a prototype tertiary device for proton beam stereotactic radiosurgery. (16th June 2021)

• Record Type: Journal Article
• Authors: Willoughby, T R; Boczkowski, A; Meeks, S L; Bova, F J; Zeidan, O A; Erhart, K; Kelly, P
• Is Part Of: Biomedical physics & engineering express. Volume 7:Number 4(2021)
• Publication Date: 2021-06-16
• Subjects: radiation therapy -- stereotactic radiosurgery -- proton radiation therapy; Medical physics -- Periodicals; Biophysics -- Periodicals; Biomedical engineering -- Periodicals; Medical sciences -- Periodicals; 610.153
• DOI: 10.1088/2057-1976/ac086b
• Languages: English
• ISSNs: 2057-1976

Abstract

Abstract: Though potentially beneficial, proton beam stereotactic radiosurgery has not been adopted widely secondary to the technical challenge of safely delivering multiple focused beams of proton radiation. In this study, we describe the design and characterization of a proton beam stereotactic radiosurgery system that can be adopted by existing passive scattering systems. This system utilizes a helmet-like device in which patient-specific brass apertures required for final beam collimation are positioned on a scaffold that is separate from the treatment gantry. The proton snout is then fitted with a generic aperture to focus the primary proton beam onto the patient specific apertures that are in the helmet-like device. The patient-specific apertures can all be placed at the start of the treatment, thus treatment with multiple beams can be accomplished without the delay of switching the apertures. In this report we describe a prototype design of this collimation system and dosimetric testing to verify efficacy. Subsequently, we describe a custom 3D printing of a prototype device and report on overall localization accuracy using Winston-Lutz tests. Our results show that it is possible to develop an add-on device for proton beam radiosurgery that is safe and efficient and capable of wide adoption on existing proton delivery systems.