A Heuristic Framework for Image Filtering and Segmentation: Application to Blood Vessel Immunohistochemistry. (27th December 2015)

• Record Type: Journal Article
• Authors: Tsou, Chi-Hsuan; Lu, Yi-Chien; Yuan, Ang; Chang, Yeun-Chung; Chen, Chung-Ming
• Other Names: Tuccari Giovanni Academic Editor.
• Is Part Of: Analytical cellular pathology. Volume 2015(2015)
• Publication Date: 2015-12-27
• Subjects: Pathology, Cellular -- Periodicals; Cytology -- Periodicals; Oncology -- Periodicals; Cancer -- Cytopathology -- Periodicals; Cancer -- Cytopathology; Cytology; Oncology; Pathology, Cellular; Cell Transformation, Neoplastic; Cells -- pathology; Cytological Techniques; Genetic Techniques; Periodicals; 571.936
• DOI: 10.1155/2015/589158
• Languages: English
• ISSNs: 2210-7177

Abstract

Abstract : The blood vessel density in a cancerous tissue sample may represent increased levels of tumor growth. However, identifying blood vessels in the histological (tissue) image is difficult and time-consuming and depends heavily on the observer's experience. To overcome this drawback, computer-aided image analysis frameworks have been investigated in order to boost object identification in histological images. We present a novel algorithm to automatically abstract the salient regions in blood vessel images. Experimental results show that the proposed framework is capable of deriving vessel boundaries that are comparable to those demarcated manually, even for vessel regions with weak contrast between the object boundaries and background clutter.