Selection and timing for invasive therapy in non-ST-segment-elevation acute coronary syndrome. (April 2013)

• Record Type: Journal Article
• Authors: Meier, Pascal; Fröhlich, Georg M; Meller, Stephanie; Palma, Rodney De; Lansky, Alexandra J
• Is Part Of: Expert review of cardiovascular therapy. Volume 11:Number 4(2013)
• Page Start: 437
• Page End: 445
• Publication Date: 2013-04
• Subjects: acute coronary syndrome -- gender -- non-ST-segment-elevation infarction -- percutaneous coronary intervention -- timing; Cardiovascular agents -- Research -- Periodicals; 616.12061
• DOI: 10.1586/erc.13.23
• Languages: English
• ISSNs: 1477-9072

Abstract

While outcomes for ST-segment-elevation myocardial infarction has significantly decreased over the last years, patients presenting with non-ST-segment-elevation acute coronary syndromes (NSTEACS) still have a rather high mortality. Longer term mortality over 4 years is about double the mortality after a ST-segment-elevation myocardial infarction. The reason for the poorer prognosis is unclear but is very likely to be partially explained by the generally older age of NSTEACS patients. The optimal therapy for NSTEACS is less well defined. In this review, the authors specifically discuss the role of coronary angiography, how to decide which patient should undergo this procedure and whether there is an optimal time point. The review provides an up-to-date discussion about the best treatment strategies for NSTEACS.