The role of drug-eluting stents for the treatment of coronary chronic total occlusions. (October 2013)

• Record Type: Journal Article
• Authors: Brilakis, Emmanouil S; Kotsia, Anna; Luna, Michael; Garcia, Santiago; Abdullah, Shuaib M; Banerjee, Subhash
• Is Part Of: Expert review of cardiovascular therapy. Volume 11:Number 10(2013)
• Page Start: 1349
• Page End: 1358
• Publication Date: 2013-10
• Subjects: chronic total occlusion -- drug-eluting stents -- percutaneous coronary intervention; Cardiovascular agents -- Research -- Periodicals; 616.12061
• DOI: 10.1586/14779072.2013.838142
• Languages: English
• ISSNs: 1477-9072

Abstract

First generation drug-eluting stents (DES) had a major impact on our capacity to percutaneously treat coronary chronic total occlusions by significantly reducing the risk for in-stent restenosis compared to bare metal stents. Second generation drug-eluting stents further improved our capacity to treat these complex lesions by providing improved deliverability and enhanced efficacy and safety. The ongoing development of bioabsorbable stents will likely be the next major advancement to improve the durability of chronic total occlusion interventions.