Biosensing Detection of the SARS-CoV-2 D614G Mutation. Issue 4 (April 2021)

• Record Type: Journal Article
• Authors: Zhang, Yang; Xi, Hui; Juhas, Mario
• Is Part Of: Trends in genetics. Volume 37:Issue 4(2021)
• Page Start: 299
• Page End: 302
• Publication Date: 2021-04
• Subjects: spike -- loop-mediated isothermal amplification (LAMP) -- restriction endonucleases -- CRISPR-Cas -- nanopore -- hybridization; Genetics -- Periodicals; 576.5
• DOI: 10.1016/j.tig.2020.12.004
• Languages: English
• ISSNs: 0168-9525

Abstract

Abstract : The emergence of a mutant strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with an amino acid change from aspartate to a glycine residue at position 614 (D614G) has been reported and this mutant appears to be now dominant in the pandemic. Efficient detection of the SARS-CoV-2 D614G mutant by biosensing technologies is therefore crucial for the control of the pandemic.