Viruses such as SARS-CoV-2 can be partially shielded from UV radiation when in particles generated by sneezing or coughing: Numerical simulations. (March 2021)

• Record Type: Journal Article
• Authors: Doughty, David C.; Hill, Steven C.; Mackowski, Daniel W.
• Is Part Of: Journal of quantitative spectroscopy & radiative transfer. Volume 262(2021)
• Publication Date: 2021-03
• Subjects: SARS CoV-2 -- UV inactivation -- Disinfection -- Respiratory droplets -- Shielding -- Light scattering; Spectrum analysis -- Periodicals; Radiation -- Periodicals; Analyse spectrale -- Périodiques; Rayonnement -- Périodiques; Radiation; Spectrum analysis; Periodicals; 543.0858
• DOI: 10.1016/j.jqsrt.2020.107489
• Languages: English
• ISSNs: 0022-4073

Abstract

Highlights: UV intensities in virions in particles can be reduced by refraction and absorption. Virions in dry particles are modeled with the Multi-Sphere T-Matrix method (MSTM). UV intensity in a virion in a particle is compared to a single virion on a surface. In 9µm droplets at 260nm, 18% of virions had intensity< 0.01 the single virion UV. Shielding is reduced by illuminating a droplet from separated incident directions. Abstract: UV radiation can inactivate viruses such as SARS-CoV-2. However, designing effective UV germicidal irradiation (UVGI) systems can be difficult because the effects of dried respiratory droplets and other fomites on UV light intensities are poorly understood. Numerical modeling of UV intensities inside virus-containing particles on surfaces can increase understanding of these possible reductions in UV intensity. We model UV intensities within spherical approximations of virions randomly positioned within spherical particles. The model virions and dried particles have sizes and optical properties to approximate SARS-CoV-2 and dried particles formed from respiratory droplets, respectively. In 1-, 5- and 9-µm diameter particles on a surface, illuminated by 260-nm UV light from a direction perpendicular to the surface, 0%, 10% and 18% (respectively) of simulated virions are exposed to intensities less than 1/100 th of intensities in individually exposed virions (i.e., they are partially shielded). Even for 302-nm light (simulating sunlight), where absorption is small, 0% and 11% of virions in 1- and 9-µm particles have exposures 1/100 th those of individually exposed virions. Shielding is small to negligible in sub-micron particles. Results show that shielding of virions in a particle can be reduced by illuminating a particle either from multiple widely separated incident directions, or by illuminating a particle rotating in air for a time sufficient to rotate through enough orientations. Because highly UV-reflective paints and surfaces can increase the angular ranges of illumination and the intensities within particles, they appear likely to be useful for reducing shielding of virions embedded within particles.