A case of T2 adenosquamous carcinoma of the tongue with unusual secondary cervical lymph nodes metastases. Issue 2 (March 2021)

• Record Type: Journal Article
• Authors: Inomata, Toru; Tanaka, Jumpei; Tanaka, Naruhisa; Fushimi, Chihiro; Kurosaka, Masao
• Is Part Of: Journal of oral and maxillofacial surgery, medicine, and pathology. Volume 33:Issue 2(2021)
• Page Start: 178
• Page End: 182
• Publication Date: 2021-03
• Subjects: Adenosquamous carcinoma -- Tongue -- Secondary cervical lymph node metastasis -- Squamous cell carcinoma -- Adenocarcinoma; Mouth -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Oral medicine -- Periodicals; Mouth -- Diseases -- Pathogenesis -- Periodicals; Surgery, Oral -- Periodicals; Oral Medicine -- Periodicals; Pathology, Oral -- Periodicals; Face -- Surgery; Maxilla -- Surgery; Mouth -- Diseases -- Pathogenesis; Mouth -- Surgery; Oral medicine; Electronic journals -- Sciences; Electronic journals -- Medicine; Periodicals; 617.522059
• DOI: 10.1016/j.ajoms.2020.10.005
• Languages: English
• ISSNs: 2212-5566

Abstract

Abstract: Adenosquamous carcinoma is a rare malignant tumor in the oral region. We encountered a case of T2 adenosquamous carcinoma of the tongue with unusual secondary cervical lymph nodes metastases. A 45-year-old man was admitted to our hospital with a complaint of pain in the right side tongue in November 2016. A partial glossectomy was performed with a diagnosis of right side tongue cancer (cT2N0M0, squamous cell carcinoma) based on image findings and histopathological examination. Postoperative six months, no clear metastasis was observed, but total neck dissection was performed in July 2017 due to subjective symptoms. Histopathological examination of metastatic lymph nodes revealed mucus-producing cells and CK7-positive cells, and the diagnosis was cervical lymph nodes metastases of adenosquamous carcinoma of the tongue. chemoradiotherapy with cisplatin was performed because extranodal extension was observed. After that, cetuximab and paclitaxel combination therapy was started because of left lung metastasis, but in July 2018, he became PD and in September, his general condition deteriorated and he died asleep.